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Improving the microbiome with prebiotics during cancer treatment- acute leukemia

Phase 1
Conditions
haematological cancer
acute leukemia
Blood - Haematological diseases
Diet and Nutrition - Other diet and nutrition disorders
Cancer - Leukaemia - Acute leukaemia
Registration Number
ACTRN12624000792527
Lead Sponsor
Metro North Hospital and Health Service
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

•age 18 years or older
•newly diagnosed acute leukemia or myelodysplasia undergoing high intensity
intravenous induction chemotherapy at the Royal Brisbane and Women’s Hospital
(RBWH)
•ability to provide written informed consent

Exclusion Criteria

•inflammatory bowel disease
•formal diagnosis of irritable bowel syndrome
•gastrointestinal resection
•ileostomy or colostomy
•any bariatric surgery including gastric bypass surgery, sleeve gastrectomy and gastric
band
•a contraindication to a high fibre diet (e.g. active diverticulitis or bowel obstruction)
•allergy/ intolerance to any ingredient in the fibre supplement
•current and planned ongoing consumption of probiotic or prebiotic supplement
•hepatitis B, hepatitis C or HIV infection unless viral load negative
•on carbamazepine
•inability to provide written informed consent

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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