Comparison of a Face Cream Plus a Laser Procedure and Face Cream Alone in Treatment of Excessive Face Hairs in Female

Phase 4

Recruiting

• Conditions: Hirsuitism
• Interventions: Radiation: Instense pulsed light; Drug: Eflornithine Topical

• Registration Number: NCT06976424
• Lead Sponsor: Khyber Teaching Hospital

Brief Summary

The study compares the effects of a cream alone and a combined effect of cream and laser for the treatment of excessive facial hairs in women .

Detailed Description

Hirsuitism refers to excessive terminal hairs in females, following a distribution pattern typically associated with male. It is associated with either increase response of hair follicles to androgen or either increase level of circulating androgens.The treatment options available are topical creams like eflornithine and laser treatments for hair removal. This study aims to conduct the comparison of a eflornithine cream and intense pulsed light laser versus eflornithine cream alone for the treatment of excessive facial hairs.

Study Timeline

• Study First Submitted: 2025-05-09
• Study First Submitted QC: 2025-05-15
• Study First Posted: 2025-05-16
• Status Verified: 2025-07
• Last Update Submitted: 2025-07-02
• Last Update Posted: 2025-07-03
• Study Start: 2025-07-15
• Primary Completion: 2025-12-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 122

Inclusion Criteria

Gender (Female) Age between 18-45 Years Women with hirsutism as mentioned in the operational definition

Exclusion Criteria

Pregnant women Women with severe acne Women with immunodeficiency

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
GroupA	Instense pulsed light	This group is treated with combination of eflornithine cream and intense pulsed light for a period of three month.
GroupA	Eflornithine Topical	This group is treated with combination of eflornithine cream and intense pulsed light for a period of three month.
Group B	Eflornithine Topical	This group is treated with eflornithine cream twice daily only for a period of three month

Primary Outcome Measures

Name	Time	Method
Efficacy of treatment	3 months	Efficacy of treatment is defined as complete clearance of excessive hairs assesed on the basis of 4- level scale ranging 0 to 3 after 3 months of administration of the treatment in both groups.; Clear is grade 3 Marked improvement is grade2 Improved is grade1 No improvement is grade 0

Trial Locations

Locations (2)

Khyber Teaching Hospital; 🇵🇰 Peshawar, KPK, Pakistan

Khyber Teachinng Hospital; 🇵🇰 Peshawar, KPK, Pakistan