Extubation in children with a high risk for postoperative respiratory complications –awake or anesthetized?

Not Applicable

Completed

• Conditions: Anaesthesiology - Anaesthetics; respiratory complications in paediatric anaesthesia

• Registration Number: ACTRN12609000291280
• Lead Sponsor: Britta von Ungern-Sternberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-05-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Children, aged 0 to 16 years, male or female with one or more of the following risk factors (I-III)
I.Airway susceptibility as defined as 1 or more of the following
a.Cold or flu in the last two weeks
b.Wheezing > 3 times in the last 12 months
c.Wheezing at exercise
d.Nocturnal dry cough
II.Current or past eczema
III.Positive family history as defined as 1 or more of the following
a.=2 family members with asthma
b.=2 family members with eczema
c.=2 family members with hayfever
d.Mother or mother and father smoking

Exclusion Criteria

Known cardiac disease, airway or thoracic malformations, need for premedication with midazolam, contraindication for deep extubation (e.g. gastrooesophageal reflux).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcomes will be the total of respiratory complications in the perioperative period.<br><br>Presence of perioperative respiratory complication as defined one or more of the following:<br>Bronchospasm, laryngospasm, severe coughing, desaturation < 95%, airway obstruction and/or stridor.<br><br>Laryngospasm is defined as a complete airway obstruction associated with muscle rigidity of the abdominal and chest walls. Bronchospasm is defined as the occurrence of an increased respiratory effort, especially during expiration, and wheeze on auscultation. Airway obstruction is defined as the presence of partial airway obstruction in combination with a snoring noise and respiratory efforts. Assessement via clinical examination and observation. [Respiratory complications will be monitored continuously in the perioperative period]

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes will be the occurrence of the individual respiratory complication. Presence of perioperative respiratory complication as defined one or more of the following:<br>Bronchospasm, laryngospasm, severe coughing, desaturation < 95%, airway obstruction and/or stridor.<br><br>Laryngospasm is defined as a complete airway obstruction associated with muscle rigidity of the abdominal and chest walls. Bronchospasm is defined as the occurrence of an increased respiratory effort, especially during expiration, and wheeze on auscultation. Airway obstruction is defined as the presence of partial airway obstruction in combination with a snoring noise and respiratory efforts. Assessement via clinical examination and observation. [Respiratory complications will be monitored continuously in the perioperative period.<br><br>]