A comparison of the effects of Triamcinolone and Dexmedetomidine and Magnesium sulfate in caudal neuroplasty in chronic low back pai

Phase 1

Conditions: ow Back Pain.
Low back pain
M54.5

Registration Number: IRCT20111102007984N32

Lead Sponsor: Iran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 60

Inclusion Criteria

Chronic low back pain more than six months +/- radiculopathyModerate to severe pain score (> 3, based on the Visual Analog Scale)Being at the age of 40-70 years
Inadequate response to conservative and physiotherapy treatments after three monthsAmerican Anesthesiologists Classification (ASA) I-IIDisc protrusion in MRI

Exclusion Criteria

Severe canal stenosis (more than two thirds in axial MRI view)
Sequestrated disc (fragmented)
Decreased disc height more than 60%
Sever spinal deformity
Spinal tumors
Vertebral fracture
Spondylolisthesis Grade>2
Local or systemic infection
Taking anticoagulants
Drug abuse
History of drug reaction
Sever psychological disorders
Pregnancy and lactation
Severe or sudden neurological deficit such as urinary or fecal incontinence
Body Mass Index (BMI) > 35
Patient's refusal
Diabetes mellitus
MRI contraindications (cardiac pacemaker, defibrillator, aortic aneurysm clips)
Impossible prone positioning

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual analog scale. Timepoint: At the beginning of the study (before the intervention) and 14, 30, 90 and 180 days after the intervention. Method of measurement: Visual Analogue Scale.;Oswestry Disability Index. Timepoint: At the beginning of the study (before the intervention) and 14, 30, 90 and 180 days after the intervention. Method of measurement: Oswestry Low Back Pain Disability Questionnaire.

Secondary Outcome Measures

Name	Time	Method
The amount of painkiller used. Timepoint: At the beginning of the study (before the intervention) and 14, 30, 90 and 180 days after the intervention. Method of measurement: Preset form for recording the amount of painkiller used.