Optimizing Antithrombotic Care in patients with AtriaL fibrillatiON and coronary stEnt study

Not Applicable

• Conditions: Atrial fibrillation (AF) Coronary artery disease post stenting

• Registration Number: JPRN-UMIN000010900
• Lead Sponsor: Kyoto University Graduate School of Medicine

Brief Summary

During a median follow-up interval of 2.5 years, the primary end point occurred in 54 patients (15.7%) in the OAC-alone group and in 47 patients (13.6%) in the combined OAC and APT group (hazard ratio, 1.16; P=0.20 for noninferiority, P=0.45 for superiority). The major secondary end point occurred in 67 patients (19.5%) in the OAC-alone group and in 67 patients (19.4%) in the combined OAC and APT group (hazard ratio, 0.99; P=0.016 for noninferiority, P=0.96 for superiority).

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-06-10
• Study Completion: 2018-06-30
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 690

Inclusion Criteria

Not provided

Exclusion Criteria

1. Patients who underwent PCI including balloon angioplasty alone within the past 12 months. 2. Patients in whom OAC is scheduled to be discontinued during the follow-up period. 3. Patients with a past history of ST. 4. Patients with a planned coronary revascularization. 5. Patients with a planned cardiovascular or non-cardiovascular surgery. 6. Patients with expectation of survival less than one year.

Study & Design

• Study Type: Interventional
• Study Design: Not specified