Effects of PRJ-205 on Performance in Trained Young Subjects After Acute and Chronic Intake of the Study Product
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Aerobic performance determined by VO2max
研究概览
简要总结
Compare a dietary supplement (PRJ-205) and placebo during 1 or 4 days on aerobic exercise performance, oxidative stress and muscle damage.
The hypothesis is that supplementation with PRJ-205 improve aerobic performance
详细描述
Twenty young active males will be recruited and randomized to either placebo or PRJ-205. Subjects will take the designated treatment in an acute dosage and chronically, 4 days of treatment.
They will undergo 3 exercise tasks (before the administration of the product, 1.5h after the acute administration of the product and after 4 days of treatment). VO2max and anaerobic threshold will be measured during the tests. Blood samples will be taken to measure muscle damage and oxidative stress.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Physically active
排除标准
- •known cardiovascular, pulmonary or metabolic disease
- •any medical condition that could affect the development and safety of the exercise task
研究组 & 干预措施
Treated
Treated volunteers will be administered one dose of PRJ-205 1,5 hours before the exercise task for the acute testing and will be taking one dose per day of PRJ-205 for 4 days for the chronic testing.
干预措施: PRJ-205 (Dietary Supplement)
Placebo
Placebo volunteers will be administered one dose of placebo 1,5 hours before the exercise task for the acute testing and will be taking one dose per day of placebo for 4 days for the chronic testing.
干预措施: Placebo (Other)
结局指标
主要结局
Aerobic performance determined by VO2max
时间窗: 4 days
次要结局
- Pressure pain threshold of calf muscle(4 days)
- Serum markers of muscular damage(4 days)
- Oxidative stress parameters(4 days)