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Clinical Trials/NCT02192710
NCT02192710
Completed
Phase 3

Reduction of Preoperative Anxiety in Children: Electronic Tab vs Midazolam

Hospices Civils de Lyon1 site in 1 country118 target enrollmentMay 1, 2013

Overview

Phase
Phase 3
Intervention
Midazolam oral intake
Conditions
Paediatric Outpatient Surgery
Sponsor
Hospices Civils de Lyon
Enrollment
118
Locations
1
Primary Endpoint
Patient's level of anxiety
Status
Completed
Last Updated
4 months ago

Overview

Brief Summary

Rationale:

The most frequently used means to prevent pre-anaesthetic anxiety in children is a drug premedication. Midazolam, a benzodiazepine, is mainly used. It requires time for action, so coordination between departments and operating room, exposed to the risks of side effects and failure and this variability action. Alternative means were evaluated, such as the presence of parents during anaesthetic mask induction, distraction by clowns, hypnosis or video games.

Electronic tabs are small devices; light, easy to use with age-specific and interactive programs. Our hypothesis is that these electronic tabs are more effective in reducing anxiety and distract children compare to preoperative medication.

Methods: This is a monocentric, randomized, open-label study comparing patients aged 4 to 10 years old programmed for a short term and low level of pain outpatient surgery. My pass score will be measured when arriving at the hospital, at the time of the separation with the parents, at the time of the anaesthetic mask induction and after the surgery.

118 patients will be randomized as follows :

  • Arm 1 : Hypnovel® (midazolam)
  • Arm 2 : Electronic tab The recruitment is performed by general practitioners in the Lyon area.
Registry
clinicaltrials.gov
Start Date
May 1, 2013
End Date
April 1, 2014
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Girls and boys aged 4 to 10 years,
  • American Society of Anesthesiologists Score between 1 and 3,
  • programmed outpatient surgery for a short term and low level of pain
  • Infection with influenza A virus confirmed with a quick diagnostic test,
  • informed consent from both parents

Exclusion Criteria

  • patients younger than 4 or older than 10 years old
  • preexisting psychiatric disorder with pedo-psychiatric follow-up
  • children with intellectual disability
  • psychotropic referred to anxiolytic and / or antipsychotic
  • history of surgery (n\>=3)
  • refusal to participate

Arms & Interventions

Hypnovel® (midazolam)

Midazolam oral intake before anesthesia

Intervention: Midazolam oral intake

Electronic tab

Intervention: electronic tab

Outcomes

Primary Outcomes

Patient's level of anxiety

Time Frame: at day 1

Comparison of m-YPAS score between the 2 arms at the time of anaesthetic mask induction (H0)

Secondary Outcomes

  • Parents' level of anxiety(Up to 2 weeks after Day 1)
  • Satisfaction of patients, parents and medical team(at day 1)
  • Patient's level of anxiety(At day 1)

Study Sites (1)

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