Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 593
- 试验地点
- 2
- 主要终点
- Number of Participants With Decrease in Knee Valgus Measurement
研究概览
简要总结
Females who participate in cutting and landing sports suffer anterior cruciate ligament (ACL) injuries at a 2 to 10-fold greater rate than males participating in the same high-risk sports. Fifty to 100 percent of ACL injured females will suffer osteoarthritis of the injured knee within one to two decades of the injury. External knee abduction moment (LOAD) predicts ACL injury with high sensitivity and specificity in female athletes. Control of lateral trunk motion (LTM) also predicts ACL injury with similar levels of sensitivity and specificity in female athletes. These predictors may be linked, as lateral positioning of the trunk can create high knee abduction load via both biomechanical and neuromuscular mechanisms. The mechanism of ACL injury in females include high knee LOAD and high LTM, with the majority of body weight shifted over the injured limb and the foot positioned lateral to the body's center of mass. An unanticipated perturbation is also often a contributor to the injury mechanism. LTM may result in increased knee LOAD by increasing the lateral position and magnitude of the GRF vector (ΔGRFv) or by increasing reactive hip adductor torque (HAdT). Our long-term objectives are to determine the mechanisms that cause ACL injury in female athletes and to develop neuromuscular training (NMT) interventions that specifically target these mechanisms. If the objectives of this proposal are achieved, an evidence-based NMT intervention will be developed and made available nationally that will effectively and efficiently reduce ACL injury risk in high-risk female athletes. The major goal of this proposal is to determine if increased LTM increases coronal plane knee load in high-risk groups of female athletes.
详细描述
- Specific Aim 1 Determine the mechanisms by which trunk motion increases knee load in females.
Rationale Aim 1 Knee external abduction moment (LOAD) and lateral trunk motion (LTM) are known to be strong predictors of ACL injury risk in female athletes, but it is not known whether these predictors are linked and which athletes are at increased risk. In addition, we do not know the specific neuromuscular mechanisms that predispose these athletes to greater risk of injury. Neuromuscular control of the trunk will be examined relative to GRF position and magnitude, hip torque and knee LOAD. We will determine if increased ΔGRFv and increased relative hip adductor torque (HAdT) underlie increased knee LOAD in females.
Central Hypothesis Aim 1 Lateral trunk motion will increase knee LOAD in female athletes by increased ΔGRFv, increased HAdT or by a combination of these two mechanisms during cutting and landing.
Hypothesis 1.1. Increased LTM induced by unanticipated lateral cutting will increase knee LOAD by increasing ΔGRFv, adjusting for HAdT, in female athletes.
Hypothesis 1.2. Increased LTM induced by single-leg medial drop landing will increase knee LOAD by increasing HAdT, adjusting for ΔGRFv, in female athletes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 10 Years 至 19 Years(Child, Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Soccer, Basketball, or Volleyball athlete
- •Attends Middle School or High School in Boone County or Fayette County KY
排除标准
- 未提供
结局指标
主要结局
Number of Participants With Decrease in Knee Valgus Measurement
时间窗: 2 years
determine biomechanical risk factors for ACL injury and determine if participation in NMT reduces risk factors compared to sham (speed training)
次要结局
未报告次要终点
