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Clinical Trials/NCT04580940
NCT04580940
Completed
Not Applicable

Flexible Percutaneous Transhepatic Cholangiopancreatoscopy (PTCS) in Complex Pancreaticobiliary Disease

Boston Scientific Corporation7 sites in 7 countries50 target enrollmentJuly 27, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pancreatic Diseases
Sponsor
Boston Scientific Corporation
Enrollment
50
Locations
7
Primary Endpoint
Achieving clinical intent of procedure as indicated
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

To document the clinical utility of percutaneous cholangiopancreatoscopy using a thin, disposable, flexible endoscope for evaluation and treatment of complex pancreaticobiliary disease in a prospective, multi-center case series

Detailed Description

This case series aims to illustrate the clinical utility of percutaneous transhepatic cholangiopancreatoscopy using a thin, disposable, flexible endoscope performed by gastroenterological endoscopists and/or interventional radiologists in procedures including but not limited to: * PTCS for tissue diagnosis in cases of surgically or pathologically-altered anatomy, * PTCS for stone removal after surgically or pathologically-altered anatomy, * Percutaneous rendezvous to aid ERCP after failed endoscopic cannulation, * Percutaneous delivery of palliative intraluminal brachytherapy, * Intra-procedural percutaneous salvage procedures when an initial route of access fails

Registry
clinicaltrials.gov
Start Date
July 27, 2021
End Date
January 14, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Scheduled for a percutaneous transhepatic procedure to access the pancreaticobiliary anatomy that will accommodate passage of SpyGlass™ Discover Digital Catheter per local standard of practice
  • Written informed consent from patient or legally authorized representative of the patient

Exclusion Criteria

  • Contraindication for cholangiopancreatoscopy
  • Subjects with unresolved adverse event(s) associated with prior percutaneous pancreaticobiliary ductal access
  • \<18 years of age
  • Potentially vulnerable subjects, including, but not limited to pregnant women

Outcomes

Primary Outcomes

Achieving clinical intent of procedure as indicated

Time Frame: 1 month

Physicians will report achieving clinical success by recording the completed procedures compared to procedures planned by 30 days (+/- 3 days) after index PTCS.

Secondary Outcomes

  • Number of Adverse Events(1 month)
  • Technical success(During index procedure)
  • Procedural Time(During index procedure)
  • Endoscopist rating(During index procedure)
  • Number of PTCS procedures(1 month)

Study Sites (7)

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