Role of Nocturnal Respiratory Disorders on Ischemic Stroke Occurrence
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 289
- 试验地点
- 1
- 主要终点
- Stroke recurrence
研究概览
简要总结
Stroke is the third leading cause of death in industrialized countries and the first cause of handicap in adults. Several stroke risk factors were identified such as high blood pressure, diabetes mellitus, hypercholesterolemia or cardiac arrhythmias. Sleep respiratory disorders have been found to be frequent among patients with stroke. Among them obstructive sleep apnea (OSA) syndrome seems to be the most important due to its association with high blood pressure and atrial fibrillation.
Stroke can be responsible of central apneas, therefore the differential diagnosis between central apneas and pure OSA after stroke is sometimes difficult. The misidentification of OSA can explain the poor tolerance of CPAP treatment by these patients. The purpose of the present study is to investigate the association between pre-stroke OSA syndrome OSA diagnosed on specific scales and confirmed by polygraphic studies and stroke occurrence.
详细描述
• Principal Objective : Investigate the association between obstructive sleep apnea diagnosed and hemispheric ischemic stroke
• Secondary Objective :
Evaluate the relation between obstructive sleep apnea and:
-
stroke mechanisms
-
stroke prognosis
-
post-stroke tolerance to CPAP treatment.
-
Study design :
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Stroke recurrence
时间窗: 3 months
次要结局
- Stroke outcome (Rankin, Barthel) Stroke mechanism CPAP tolerance(3 months)
