The Evaluation of Chenopodium Formosanum and Fagopyrum Esculentum Extract on Anti-aging Effect
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The change of skin elasticity
研究概览
简要总结
To assess Chenopodium Formosanum and Fagopyrum Esculentum Extract on skin anti-aging
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged between 20-65 years old
- •Subjects must read and sign the informed consent form after the study has been fully explained.
- •Subjects are willing to cooperate and comply with all of the regulation during the trial.
- •Subject should inform to investigator immediately if adverse effect is happened.
- •Subjects are willing to avoid UV overexposure during the trial (include indoor tanning treatment).
排除标准
- •Subjects who have known cosmetic, drug or food allergies.
- •Subjects who have severe desquamation, tattoo, sunburn, peeling skin or other skin condition might impact measurement.
- •Subjects with any physical condition judged by the researcher not to be eligible for this study.
- •Subjects with uncontrollable physical condition such as high blood pressure, thyroid disease, diabetes, etc.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Those who are currently participating in other clinical trials or who have just concluded a clinical trial two weeks ago.
- •Women who have started contraceptive or change current hormone contraceptive methods within 3 months.
研究组 & 干预措施
Placebo drink
干预措施: Placebo drink (Dietary Supplement)
Chenopodium Formosanum and Fagopyrum Esculentum Extract drink
干预措施: Chenopodium Formosanum and Fagopyrum Esculentum Extract drink (Dietary Supplement)
结局指标
主要结局
The change of skin elasticity
时间窗: Change from Baseline skin elasticity at 8 weeks
Cutometer® dual MPA 580 is utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curves
The change of skin wrinkles
时间窗: Change from Baseline skin wrinkles at 8 weeks
3D Full-Face Skin Analyzer IRV is utilized to measure wrinkles. Units: arbitrary units
The change of skin moisture
时间窗: Change from Baseline skin moisture at 8 weeks
Corneometer® CM825 is utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin collagen density
时间窗: Change from Baseline skin collagen density at 8 weeks
DermaLab® combo - 20 MHz High Freq. Ultrasound probe is utilized to scan and analyze skin collagen density. Units: Intensity score
The change of skin melanin index
时间窗: Change from Baseline skin melanin index at 8 weeks
Mexameter® MX 18 is utilized to measure skin melanin index. Units: arbitrary Mexameter® units (0-999)
The change of skin brightness
时间窗: Change from Baseline skin brightness at 8 weeks
3D Full-Face Skin Analyzer IRV is utilized to measure skin brightness. Units: arbitrary units
The change of skin L*a*b* value
时间窗: Change from Baseline skin L*a*b* value at 8 weeks
Color Spectrophotometer SCM-104/108 is utilized to measure skin L\*a\*b\* value. Units: arbitrary units
The change of skin tone
时间窗: Change from Baseline skin tone at 8 weeks
3D Full-Face Skin Analyzer IRV was utilized to measure skin tone. Units: arbitrary units
次要结局
- The change of skin pores(Change from Baseline skin pores at 8 weeks)
- The change of transepidermal water loss (TEWL)(Change from Baseline TEWL at 8 weeks)
- The change of skin texture(Change from Baseline skin texture at 8 weeks)
- The change of skin spots(Change from Baseline skin spots at 8 weeks)
- The change of skin erythema level(Change from Baseline skin erythema level at 8 weeks)
- Self-assessment questionnaire(8 weeks)