A randomized, controlled, open label, triple arm, prospective clinical study for therapeutic evaluation of Qurs-e-Mafasil Jadeed with and without Hijama biâ??l Shart (Wet cupping) in knee Osteoarthritis with special reference to selective Biomarkers

Central Council for Research in Unani Medicine0 sites0 target enrollmentStarted: TBDLast updated: November 24, 2021

Trial Snapshot

No summary available.

•Patients of any sex aged 40-70 years
•Patients having Moderate to severe Knee pain (pain more than 40 mm and less than 90 mm) after 50 feet Walking on a flat surface
•Patients of Knee OA with chronicity of more or equal to 6 months
•Patients having K L Grading criteria of grades II or III
•Patients with normal laboratory values.
•Patients willing to comply with the regular treatment schedule as per protocol

•Anemia (less than 10g percent of Hb) and bleeding disorders
•Pregnant and Lactating Mothers
•Another type of arthritis, eg Rheumatoid arthritis, Psoriatic arthritis, Gouty arthritis
•Patients taking Anticoagulants, corticosteroid or NSAIDs or any other concomitant therapy
•History of Surgery, Tidal lavage/Arthroscopy of the joint involved, of affected knee within the past 1 year. Intra-articular (IA) corticosteroid injection of affected knee within a 3 months interval prior to baseline screening
•Patients with the gastro-intestinal disease, peptic ulcer and having fecal blood loss
•History of Systemic illness such as Liver, Kidney, Cardiac disorders, DM, HTN, Osteomyelitis, Tuberculosis,
•Known cases of Immunocompromised states (HIV or AIDS, etc.)/ Malignancies
•Patients who were not willing to be randomized
•Ongoing use of prohibited medication including NSAID, another oral analgesic, muscle relaxant, or a low-dose antidepressant for any chronic pain management
•Concomitant skin disease at the application site
•History of alcohol or Drug abuse, excessive smoking,
•Diagnosed neurological or psychiatric disorders

Sponsor