Acute and chronic influences of cannabidiol on the ability to regenerate after strength and endurance training
Not Applicable
- Conditions
- Muscle damage: CK and MyoInflammation: Il6 and Il 10
- Registration Number
- DRKS00018770
- Lead Sponsor
- Deutsche Sporthochschule Köln, Institut für Kreislaufforschung und Sportmedizin, Abteilung 2 Molekulare und zelluläre Sportmedizin - Zentrum für präventive Doping Forschung
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 26
Inclusion Criteria
youn healthy men and women
Exclusion Criteria
Hormone substitution, including thyroid-hormone therapy
BMI >30
smokers
unbalanced diet (e.g. vegan)
metabolic disorders
Treatment with insulin, sulfonylureas, glinides, GLP -1 analogs those in need of treatment
cardiac arrhythmias
Heart failure (EF<55)
Performance limiting PAVK
(Fontaine Stadium = II)
performance- or traininglimiting
Respiratory diseases,
performance- or traininglimiting degenerative joint diseases or muscular diseases
performance-limiting kidney disease
performance-limiting neurological
illness
oncological diseases in the Prehistory (< 5 years)
psychiatric and/or addiction disorders
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method intravenous Blood samples (9ml)<br><br>Analytics of<br>muscle damage: CK, Myo<br>inflammation: Il6 und Il10<br><br>Time Points<br>T0 (pre), T1 (+3h), T2 (+24h), T3 (+48h), T4 (+72h)
- Secondary Outcome Measures
Name Time Method Performance:<br><br>1RM back squat<br>20 sprint<br>Counter Movement Jump<br><br>Time points<br>T0 (pre), T1 (+3h), T2 (+24h), T3 (+48h), T4 (+72h)