Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis

Not Applicable

Completed

• Conditions: Interstitial Cystitis; Overactive Bladder; Bladder Pain Syndrome

• Registration Number: NCT03023241
• Lead Sponsor: Cantonal Hospital, Frauenfeld

Brief Summary

To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.

Detailed Description

Collection and analyses of bladder biopsies, bladder washings, blood and urine samples of patients with bladder pain syndrome/interstitial cystitis (BPS/IC), overactive bladder syndrome (OAB) and bladder-healthy controls. Analyses include ELISA, RT-qPCR, DNA sequencing, and immunohistochemistry techniques. Differences between patient groups are statistically evaluated.

Study Timeline

• Study Start: 2004-12
• Study First Submitted: 2017-01-13
• Study First Submitted QC: 2017-01-13
• Study First Posted: 2017-01-18
• Primary Completion: 2020-12
• Study Completion: 2021-07
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-30
• Last Update Posted: 2022-03-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

• patient with diagnosed BPS/IC, OAB or healthy controls
• included healthy controls must have another pelvic surgery planned (e.g. hysterectomy)
• being able to act and judge

Exclusion Criteria

• unstable endocrinological situation
• severe illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Identification of new diagnostic markers for BPS/IC	2 days

Secondary Outcome Measures

Name	Time	Method
Identification of molecular details that lead to BPS/IC (pathogenesis).	2 days

Trial Locations

Locations (1)

Cantonal Hospital Frauenfeld; 🇨🇭 Frauenfeld, Thurgau, Switzerland