NCT03023241CompletedNot Applicable
Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis
Cantonal Hospital, Frauenfeld2 sites in 1 country300 target enrollmentStarted: December 1, 2004Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 300
- Locations
- 2
- Primary Endpoint
- Identification of new diagnostic markers for BPS/IC
Study Overview
Brief Summary
To identify new, simple and reliable biomarkers for bladder pain syndrome/interstitial cystitis (BPS/IC) for diagnosis of this disease.
Detailed Description
Collection and analyses of bladder biopsies, bladder washings, blood and urine samples of patients with bladder pain syndrome/interstitial cystitis (BPS/IC), overactive bladder syndrome (OAB) and bladder-healthy controls. Analyses include ELISA, RT-qPCR, DNA sequencing, and immunohistochemistry techniques. Differences between patient groups are statistically evaluated.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patient with diagnosed BPS/IC, OAB or healthy controls
- •included healthy controls must have another pelvic surgery planned (e.g. hysterectomy)
- •being able to act and judge
Exclusion Criteria
- •unstable endocrinological situation
- •severe illness
Outcomes
Primary Outcomes
Identification of new diagnostic markers for BPS/IC
Time Frame: 2 days
Secondary Outcomes
- Identification of molecular details that lead to BPS/IC (pathogenesis).(2 days)
Investigators
Prof. Dr. Volker Viereck
Prof. Dr. med.
Cantonal Hospital, Frauenfeld
Study Sites (2)
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