NCT05122962
招募中
不适用
Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Tetralogy of Fallot
- 发起方
- Mayo Clinic
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Right Heart Remodeling
- 状态
- 招募中
- 最后更新
- 2个月前
概览
简要总结
This study is being done to determine the mechanism(s) contributing to the onset of symptoms (i.e. shortness of breath and/or palpitations) as well as changes in heart structure in patients with congenital heart disease (CHD)
研究者
入排标准
入选标准
- •Moderate (or greater) PR based on quantitative Doppler echocardiography.
- •Repaired TOF
- •Congenital Heart Disease diagnosis including but not limited to Ebstein's anomaly, coarctation of the aorta (COA), Fontan palliation, transposition of the great arteries, congenitally corrected transposition of the great arteries.
排除标准
- •Pregnant Women
- •Unable to undergo CMRI
结局指标
主要结局
Right Heart Remodeling
时间窗: 24 Months
Right Heart Remodeling measured via right atrial reservoir strain (%).
次要结局
- Incident arrhythmias(24 Months)
- Aerobic Capacity(24 Months)
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Early Switch from Controlled to Assisted VentilationAcute Hypoxemic Respiratory FailureMechanical VentilationNCT06438198Erasmus Medical Center20
已完成
不适用
Epidemiology of Symptomatic ArrhythmiasCardiovascular DiseasesHeart DiseasesAtrial FibrillationArrhythmiaTachycardiaTachycardia, SupraventricularNCT00005237National Heart, Lung, and Blood Institute (NHLBI)
进行中（未招募）
不适用
Correlation of the Arrhythmia Mechanism and Substrate to Ablate Persistent Atrial Fibrillation StudyPersistent Atrial FibrillationNCT02184013Ottawa Heart Institute Research Corporation52
已完成
不适用
Mechanisms in Heart Failure With Normal EFHeart FailureNCT00587808Mayo Clinic14
招募中
不适用
Ventricular Tachycardia MechanismsVentricular TachycardiaNCT05478213Emory University10