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Stimulux: Optimizing blue light exposure on the retina for non-image forming effects and visual comfort

Completed
Conditions
nvt
Registration Number
NL-OMON38764
Lead Sponsor
Janssen-Cilag
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
18
Inclusion Criteria

Healthy men and women; ages between 20-35y to avoid the lens changes that occur with aging
Subjects should be fluent in Dutch (because of the use of Dutch rating scales). Signed informed consent.

Exclusion Criteria

You suffer from (chronic) disease (physical or psychological)
You suffer from sleep disorders (mild sleep complains are not a problem)
You are visually impaired or you had undergo eye surgery in the last year (contact lenses and glasses are not a problem)
You are taking medication or have taken long-term effects medication in the 3 months prior to participation, which are known to increase the sensitivity to light (see leaflet)
You use regular sleep medication or stimulants
Two or more time zones transmeridian flights one month prior to participation
Shift work during the 3 months prior to participation
Colour blindness
Excessive daily amounts of caffeinated drinks (>8 cups/drinks per day. E.g., coffee, cola, energy drinks)
Alcohol (more than 3 glasses on a working day) or drug problems
The use of melatonin

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Study 1: pupil size changes in response to light exposure. Study 2: melatonin<br /><br>suppression in response to light </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>visual comfort, alertness and performance in response to light exposure</p><br>
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