NCT00000175终止不适用
The Effects of Sex Hormones on Cognition and Mood in Older Adults
National Institute on Aging (NIA)2 个研究点 分布在 1 个国家开始时间: 1999年11月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 试验地点
- 2
研究概览
简要总结
This study is investigating the effects of hormone replacement therapy on memory, mental abilities and mood in older adults aged 65-90. During the nine month long study, men will take testosterone for three months and women will take estrogen for three months. At four points during the study (once every three months), participants will complete a test battery and have blood drawn.
详细描述
Double-blind, placebo-controlled, crossover study investigating the effects of estrogen replacement and testosterone replacement on cognition and mood in older adults. Women who have not had a hysterectomy will be given Prempro (estrogen with progesterone to protect the uterine lining), and hysterectomized women will be given Premarin (estrogen only).
研究设计
- 研究类型
- Interventional
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 65 Years 至 90 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Women and men aged 65-90 who have not received hormone replacement for the last three months.
排除标准
- •Previous head injury with loss of consciousness for more than one hour.
- •Men with a history of prostate cancer.
- •Men on testosterone replacement within the past three months.
- •Women with a history of breast or uterine cancer.
- •Women on estrogen replacement within the past three months.
研究者
研究点 (2)
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