Development of exercise programs on spinal cord injury levels

Not Applicable

Completed

• Conditions: Injury, poisoning and certain other consequences of external causes

• Registration Number: KCT0008257
• Lead Sponsor: Yonsei University

Brief Summary

The 6-week exercise program significantly decreased the average fasting insulin (baseline: 7.5±4.7 µU/ml vs. postintervention: 4.5±2.2 µU/ml, p<0.05) and HOMA-IR (baseline: 1.5±1.0 vs. post-intervention: 0.9±0.4, p<0.05) in the exercise group, whereas there was no change in control group (between group difference, mean fasting insulin: -3.2 µU/ml, p=0.003; mean HOMA-IR: -0.66, p=0.001). In addition, muscle strength of the shoulder flexors, extensors, abductors, adductors and elbow flexors was significantly improved in the exercise group compared to the controls.A combined exercise program is effective in decreasing fasting insulin and HOMA-IR levels while improving fitness in those with SCI.

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-12-22
• Results First Posted: 2019-01-24
• Last Update Posted: 4 April 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

These inclusion criteria included:
(1) having had a SCI for more than 6 months, (2) aged between 18 and 70 years old, and (3) not having exercised on a regular basis for the six months preceding the study.

Exclusion Criteria

The exclusion criteria included:
(1) cardiovascular disease, (2) uncontrolled type 2 diabetes, (3) uncontrolled hypertension, (4) pressure ulcers, and (5) orthopedic problems.

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Body composition (height, weight, body mass index, muscle mass, body fat mass, body fat percentage, waist circumference, hip circumference, blood pressure)

Secondary Outcome Measures

Name	Time	Method
Physical fitness (Upper limb strength, cardiorespiratory fitness (Vo2 peak));Blood profile ( Total Cholesterol HDL-Cholesterol LDL-Cholesterol Triglycerides AST, ALT ,r-GTP CRP, hs-CRP Fasting glucose Fasting insulin HOMA-IR HbA1c);Mental health (health-related quality of life, anxiety and depression)