NCT07473375招募中不适用
Indicators Affecting Portal Vein Thrombosis Recanalization in Cirrhosis With Gastroesophageal Varices
Shanghai Zhongshan Hospital1 个研究点 分布在 1 个国家目标入组 1,500 人开始时间: 2017年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- PVT recanalization at 1 year
研究概览
简要总结
This is a retrospective-prospective study conducted at Zhongshan Hospital, Fudan University, to explore portal vein thrombosis (PVT) in patients with cirrhosis and gastroesophageal varices (GEV). It aimed to provide insights into the diagnosis, follow-up, and factors influencing PVT recanalization, to help patients, families, and healthcare providers understand the disease and related clinical management.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed as cirrhosis and confirmed gastroesophageal varices by endoscopy;
- •all patients were diagnosed as PVT by CTA at admission.
排除标准
- •patients with hepatocellular carcinoma;
- •patients with extrahepatic malignancies;
- •history of liver transplantation or TIPS;
- •lack of information regarding anticoagulation therapy；
- •those with cavernous transformation of the portal vein(CTPV) .
结局指标
主要结局
PVT recanalization at 1 year
时间窗: From the first abdominal imaging assessment after admission, until the occurrence of PVT recanalization at 1 year, death, or the last follow-up, whichever came first
次要结局
- Occurrence of all-cause death (competing event)(From the date of admission confirmation of PVT to the occurrence of death, or the last follow-up, whichever came first)
- PVT recanalization at 5 years(From the first abdominal imaging assessment after admission, until the occurrence of PVT recanalization at 5 year, death, or the last follow-up, whichever came first)
- Occurrence of non-improved PVT(From the date of admission confirmation of PVT to the last radiological follow-up at 1 year, or death, whichever came first)
研究者
研究点 (1)
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