NCT00361322已完成1 期
Topical Clindamycin Salicylic Acid Preparation for the Treatment of Acne Vulgaris
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Lesions count at the end of study (week 8)
研究概览
简要总结
The concept behind our study was to combine an effect of antibiotic and anti-inflammatory agents for a more efficient acne therapy directed at the factors involved in the pathophysiology of the disease. For this purpose we evaluated a combination of clindamycin phosphate and salicylic acid in a non-irritating carrier.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •mild to moderate acne vulgaris;
- •at least 5 lesions on the face;
- •a one-month wash-out period was established for any topical or systemic drug use for treatment of acne vulgaris.
排除标准
- •acne that was primarily truncal, nodular, or due to secondary causes/internal disease;
- •pregnancy, breastfeeding, or intention to become pregnant;
- •another dermatological disease of the face;
- •significant systemic disease;
- •any drug/alcohol addiction;
- •interacting medication;
- •known hypersensitivity to study medications;
- •history of chronic disease treated with medications which might affect acne condition and treatment outcome (e.g. corticosteroids, lithium, isoniazid, anti-androgens, phenytoin, phenobarbital) in the preceding month
结局指标
主要结局
Lesions count at the end of study (week 8)
Lesions count at the baseline (week 0)
次要结局
未报告次要终点
研究者
研究点 (2)
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