NCT04399213已完成不适用
Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Change in dermal blood flow induced by histamine skin pricks, compared to baseline and placebo for different doses
研究概览
简要总结
To determine the effective dose and the time course, the dermal blood flow response to histamine will be evaluated at different doses (5 µg, 15 µg and 50 µg). Histamine will be administered by a skin prick on the volar surface of subjects' forearm, alongside a negative control. Changes in dermal blood flow will be measured with laser Doppler imaging at different time points following the skin prick.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Change in dermal blood flow induced by histamine skin pricks, compared to baseline and placebo for different doses
时间窗: The dermal blood flow will be assessed before (baseline) and every 5 minutes during the hour following the skin pricks
次要结局
未报告次要终点
研究者
研究点 (2)
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