Exploring Men s Prostate Cancer Genetic Risk Perceptions and Willingness to Give a Biospecimen for Genetic Risk Testing
Overview
- Phase
- N/A
- Intervention
- Questionnaire
- Conditions
- Prostate Cancer
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Prostate Cancer Genetic Risk and Susceptibility Beliefs
- Status
- Completed
- Last Updated
- 2 months ago
Overview
Brief Summary
The exploring men's prostate cancer genetic risk perceptions and willingness to give a biospecimen for genetic risk testing study aims to assess prostate cancer genetic risk and susceptibility beliefs among unaffected men of diverse races/ethnicities who are considering undergoing prostate cancer screening and their willingness of men to provide a biospecimen (saliva sample) and test the samples for prostate cancer aggressiveness and determine risk category based on SNP genetic profile.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Racially/ethnically diverse men with emphasis on Men of African Ancestry.
- •Age 40 and older .
- •No personal prostate cancer history/diagnosis.
- •With or without family history of prostate cancer.
Exclusion Criteria
- •Previous personal Prostate Cancer history/diagnosis
- •Under 40 years of age
Arms & Interventions
Prostate Cancer Risk Group
Participants will be asked to provide saliva samples and complete a questionnaire about their Prostate Cancer Genetic Risk beliefs.
Intervention: Questionnaire
Prostate Cancer Risk Group
Participants will be asked to provide saliva samples and complete a questionnaire about their Prostate Cancer Genetic Risk beliefs.
Intervention: Saliva Sample
Outcomes
Primary Outcomes
Prostate Cancer Genetic Risk and Susceptibility Beliefs
Time Frame: Up to 6 Months
Prostate Cancer Genetic Risk and Susceptibility beliefs will be summarized based on single items on the Prostate Cancer Risk Perception Questionnaire.
Secondary Outcomes
- Polygenic Risk Score (PRS) of Saliva Samples(Up to 6 Months)