Lifestyle and Non-motor Symptom Management in Parkinson's Disease
- Conditions
- FatigueParkinson Disease
- Interventions
- Other: Semi-structured interviews and a consensus workshops using nominal group techniques.
- Registration Number
- NCT04837976
- Lead Sponsor
- Oxford Brookes University
- Brief Summary
Parkinson's Disease (PD) has generally been thought of as a movement disorder however other health-related symptoms, known as non-motor symptoms, are also very common. Non-motor symptoms can be very broad and present in numerous conditions, making identifying the symptoms of early-stage Parkinson's disease very difficult. Non-motor symptoms, including fatigue, and problems with sleep and mood, can happen decades before motor symptoms and have a greater impact on quality of life and psychological wellbeing. Despite this treatment options for non-motor symptoms are limited and therefore the development and testing of new treatments is a main priority.
Due to the limited treatments options available, self-management of symptoms through positive lifestyle changes is a warranted area of research. The perspectives amongst patients, caregivers, and HCP's regarding lifestyle behavior change and its impact on fatigue and related non-motor symptoms has yet to be investigated in detail. This study includes two stages: telephone interviews and online consensus workshops. Patients with PD whom have experience of fatigue, partners/caregivers and Healthcare professionals will be able to participate in interviews only, workshops only or both. The interviews will investigate patients, partners/caregivers and Healthcare Professionals views and priorities of lifestyle factors in the management of non-motor symptoms in Parkinson's disease as well as identifying factors that influence lifestyle changes amongst PD patients. Stage 2 will involve small consensus workshops to generate ideas and feedback related to the design and content of the soon-to be developed lifestyle program. Results from both stages of this study will be used to help develop and design a lifestyle management program for fatigue and associated non-motor symptoms in Parkinson's Disease.
- Detailed Description
Global aim: To assess stakeholders (patients, supportive individuals, and HCP's) views and priorities of lifestyle factors in the management of fatigue and related non-motor symptoms in Parkinson's disease, in addition to identifying facilitators and barriers to lifestyle-related behavior change, in order to inform the development of a subsequent lifestyle intervention.
The study consists of two stages:
1. Semi-structured interviews (lasting around 60 minutes)
2. Online consensus workshops using a nominal group technique (2x 60 minute sessions)
Setting: Both stages will be conducted remotely. For Stage 1 interviews will be conducted over the telephone (with or without videoconferencing). Stage 2 will use an online brainstorming platform to run the consensus workshop with concurrent videoconferencing.
Participants: For both stages' participants will include individuals with Parkinson's Disease, supportive individual's (partners/caregivers/family members/significant others) and healthcare professionals.
Analysis:
Stage 1- Interviews will be analyzed using thematic analysis and framework mapping onto the COM-B model. Themes will be deductively mapped onto the categories and its associated constructs of the Capability, Opportunity and Motivation to Behaviour (COM-B) model to identify specific targetable aspects of behavior that may need to be addressed in the subsequent lifestyle intervention. A secondary categorical form narrative analysis of the interviews will also be conducted to supplement the main group analysis by providing a detailed insight into the experiences and stories of participants in relation to lifestyle changes on an individual level.
Stage 2- Responses during the consensus workshop will be analyzed using frequency counts and descriptive. Data will include a complete list of ideas, scores allocated to each idea, the overall rank of each idea and any additional comments made by participants.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 41
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Individuals with Parkinson's Disease Semi-structured interviews and a consensus workshops using nominal group techniques. - Supportive individuals Semi-structured interviews and a consensus workshops using nominal group techniques. For example carers, family members or any other individual providing regular support or care to the person with Parkinson's. Healthcare Professionals Semi-structured interviews and a consensus workshops using nominal group techniques. -
- Primary Outcome Measures
Name Time Method Themes related to the views and priorities of lifestyle factors in relation to fatigue and non-motor symptom management in Parkinson's Disease. Assessed during the interview (60 minutes) after enrollment Facilitators to dietary and exercise-based lifestyle change amongst patients with Parkinson's disease. Assessed during the interview (60 minutes) after enrollment Barriers to dietary and exercise-based lifestyle change amongst patients with Parkinson's disease. Assessed during the interview (60 minutes) after enrollment Identified behavioral targets for the intervention as indicated by the mapping of themes onto the COM-B model (capability, opportunity or motivation) Assessed during the interview (60 minutes) after enrollment A list of potential methods of intervention delivery, structure and content, ranked in order of preference created during consensus workshops. From participation in the first consensus session after enrollment until session 2 (around 1-2 weeks later)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Oxford Brookes University
🇬🇧Oxford, Oxfordshire, United Kingdom