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Clinical Trials/NL-OMON34471
NL-OMON34471
Completed
Phase 2

An exploratory study to evaluate the effect of a new study product on early programming in healthy infants - EAGLE2

Danone Vitapole0 sites28 target enrollmentTBD

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
healthy subjects
Sponsor
Danone Vitapole
Enrollment
28
Status
Completed
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Interventional

Investigators

Sponsor
Danone Vitapole

Eligibility Criteria

Inclusion Criteria

  • Healthy and full\-term infants (gestational age \* 37 and \* 42 weeks)
  • Birth weight within the normal range for gestational age and sex (10th to 90th percentiles according to applicable growth charts)
  • Age \* 7 weeks at screening
  • Body weight appropriate for the individual age and sex at screening (10th to 90th percentiles according to applicable growth charts)
  • Infants who are fully formula fed or have started the transition from breast\- to formula\-feeding (indicated by the feeding of at least one bottle of infant formula in the past) and are planning to stop breastfeeding voluntarily by infant\*s age of 7 weeks
  • Written informed consent of both parent(s)/legal guardian(s)

Exclusion Criteria

  • Infants not on full formula feeding at the age of 7 weeks (to be answered latest at the age of 8 weeks (visit 2\))
  • Infants with known congenital diseases or malfunctions e.g. gastrointestinal malformations, haemophilia
  • Current or previous illnesses which could interfere with the study (e.g. prolonged severe diarrhoea, regurgitation)
  • \*Infants with abnormal growth (too slow (\< \-1SD) or too fast (\> \+1SD) weight gain) within the 10th to 90th percentiles of applicable weight\-for\-age charts for either boys or girls
  • Infants at high risk to develop an atopic disease (at least one parent or sibling with manifest atopic symptoms of hay fever, asthma or atopic dermatitis)
  • Infants needing a special diet other than standard cow\*s milk\-based infant milk formula
  • \*Infants whose mothers are known to suffer from hepatitis B, human immunodeficiency virus (HIV), high blood\-pressure, hyperlipidaemia or diabetes
  • Infants whose mother was overweight (BMI \* 27\) prior to pregnancy
  • Infants with any historical or current participation in any other study involving investigational or marketed products
  • Investigator's uncertainty about the willingness or ability of the parents to comply with the protocol requirements and instructions

Outcomes

Primary Outcomes

Not specified

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