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Treatment Patterns and Outcomes in Participants With Advanced Melanoma in Germany Using a German Database

Completed
Conditions
Advanced Melanoma
Registration Number
NCT05426239
Lead Sponsor
Bristol-Myers Squibb
Brief Summary

This study is a non-interventional retrospective observational study performed on secondary data from a German multi-site cohort registry, the German national registry of skin cancer (ADOReg).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1008
Inclusion Criteria
  • Signed informed consent for inclusion in ADOReg registry must be documented at study site
  • Diagnosis of advanced (nonresectable or metastatic) melanoma in stage III or stage IV
  • Participants received any systemic therapy to treat the advanced melanoma
  • First-line systemic treatment was initiated within the index window (19-Jun-2015 to 30-Jun-2018)
Exclusion Criteria
  • Age <18 years at index date
  • Receipt of clinical trial study drug at any time

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Overall Survival (OS)Up to a maximum of 4 years of follow-up
Secondary Outcome Measures
NameTimeMethod
Progression-Free Survival (PFS)Up to a maximum of 4 years of follow-up
Treatment-free Survival (TFS)Up to a maximum of 4 years of follow-up
Frequency of ADRsUp to a maximum of 4 years of follow-up
Duration of Response (DOR)Up to a maximum of 4 years of follow-up
Time to Treatment DiscontinuationUp to a maximum of 4 years of follow-up
Objective Response Rate (ORR)Up to a maximum of 4 years of follow-up
Resolution Rate (RR) of ADRsUp to a maximum of 4 years of follow-up
Treatment-free Interval (TFI)Up to a maximum of 4 years of follow-up
Incidence Rate (IR) of Adverse Drug Responses (ADRs)Up to a maximum of 4 years of follow-up

Trial Locations

Locations (1)

Site0001

🇩🇪

Frankfurt, Germany

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