The Effect of rTEM in the Prognosis and Severity of Sepsis Induced ARDS

Not yet recruiting

• Conditions: Sepsis
• Interventions: Other: Taking peripheral blood

• Registration Number: NCT06063707
• Lead Sponsor: Southeast University, China

Brief Summary

To observe the changes of plasma rTEM levels in patients with sepsis, sepsis induced ARDS, and to explore its clinical significance.

Detailed Description

90 patients will be included in this study. Blood samples from these patients in the first day, the third day, were maintained and tested to detect the change of rTEM level. Severity of illness and survival status of every patient were recorded within 28 days. The objective is to observe the changes of plasma rTEM levels in patients with sepsis, sepsis induced ARDS, and to explore its clinical significance.

Study Timeline

• Study First Submitted: 2023-08-31
• Study First Submitted QC: 2023-09-29
• Status Verified: 2023-10
• Study Start: 2023-10-01
• Last Update Submitted: 2023-10-01
• Study First Posted: 2023-10-02
• Last Update Posted: 2023-10-03
• Primary Completion: 2024-08-01
• Study Completion: 2024-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Diagnosed as Sepsis 3.0 Patients signing informed consent

Exclusion Criteria

Pregnant women Patients with tumor、hepatitis、liver cirrhosis、acute myocardial infarction、chronic renal tubular nephritis、interstitial pneumonia、acute pancreatitis、systemic lupus erythenatosus、ulcerative colitis、crohn's disease、HELLP syndrome

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Survivors	Taking peripheral blood	Sepsis induced ARDS patients who survived
Nonsurvivors	Taking peripheral blood	Sepsis induced ARDS patients who not survived

Primary Outcome Measures

Name	Time	Method
Mortality	28 day	28day mortality