Study of mature and immature red blood cell indices in iron deficiency status

Recruiting

Brief Summary: Iron status reflects balance between rate of erythropoiesis and iron stores in the

body.Iron deficiency is one of the most common nutritional deficiency in world

and a leading cause of anemia. Anemia is very common and significant in

country like India, Hence early diagnosis is of utmost importance .Anemia is

defined as decreased concentration of Hemoglobin(Hb) in the blood, cutoff value

depending on age and gender.In practice Anemia is usually diagnosed based on

reduction of Hematocrit and Hb concentration ,but isolated Hb measurement has

both low specificity and low sensitivity. Several studies in the field of iron

metabolism and erythropoiesis are modifying the traditional concepts on anemia.

These studies point out the need for reliable diagnostic parameters that allow better

evaluation of the causes underlying apparently similar clinical conditions. Thus

implying stronger collaboration between laboratory professionals and clinicians in

order to optimize early diagnosis of anemia by new analytical parameters viz.

RSf (Red cell size factor) and LHD %.

Recruitment & Eligibility

Inclusion Criteria

hemoglobin,MCV,MRV,MCHC,MCH,Rsf,LDH%.

Exclusion Criteria

pediatric age group,normocytic normochromic anemia, macrocytic anemia,anemias with bleeding disorders , chronic anemias.

Primary Outcome Measures

Name	Time	Method
Rsf and LHD%	2 YEARS

Secondary Outcome Measures

Name	Time	Method
MC,MRV,MCHC	2 YEARS

Locations (1): Hematology division, Central lab , Father muller medical college
🇮🇳
Kannada, KARNATAKA, India
Hematology division, Central lab , Father muller medical college
🇮🇳Kannada, KARNATAKA, India
Dr Salman Akther
Principal investigator
8152840903
dr.salmanakhter25@gmail.com