Family-based Health Education Program and Zinc Supplementation for Stunted Mother and Its Impact on Biomarker of Growth in Baby
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 126
- 试验地点
- 2
- 主要终点
- Infant weight
研究概览
简要总结
Background :
It is important to tackle the issue of malnutrition at an early stage. A stunted mother has a tendency of having adverse neonatal outcomes including growth restriction. The multidisciplinary intervention followed by micronutrient supplementation is developed to prevent these adverse outcomes. Zinc has been associated with better neonatal growth and brain growth. This study aims to assess the impact of family-based health education programs plus zinc supplementation on the important biomarker of pregnancy and neonatal growth.
Objective :
- To assess the impact of Family-based health education programs plus zinc supplementation on the outcome of pregnancy in stunted mother
-
- To assess the impact of Family-based health education programs plus zinc supplementation on the outcome of neonatal growth in stunted mother
Methodology :
A Quasi-experimental study involving stunted pregnant mother with parallel intervention
Hypothesis :
Mother who receives the intervention will have the better maternal and neonatal outcome
详细描述
Details of Family-Based Health Education Program + Zinc :
- Home-visit and health promotion by trained midwives
- Supervision by health volunteer
- Zinc Supplementation
General target population :
- Stunted pregnant mother on the third trimester of pregnancy
- Conducted in Primary Health Care Center
Design of Study :
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Body height is less than 150 cm
- •Upper Arm Circumference less than 23.5 cm
- •Family income is less than Rp 2,500,000,- following the minimum wage of targeted area
- •24-26 weeks pregnant.
排除标准
- •has pregnancy complications
- •multiple infants
- •refuse to follow the protocol
结局指标
主要结局
Infant weight
时间窗: changes of weight at birth up to 6 months
This includes weight at birth, weight at 3 months and 6 months
Infant Length
时间窗: changes of length at birth up to 6 months
This includes length of body at birth, at 3 months and 6 months
次要结局
- Hemoglobin level of mother(changes of hemoglobin level of mother from the baseline to delivery time)
- Insulin-like growth factor 1 (IGF-1) of infant(changes of IGF-1 level of infant from the day of birth to 6 months)
- Tumor Growth Factor Beta 1 (TGF beta 1) of infant(changes of TGF Beta 1 level of infant from the day of birth to 6 months)
- Zinc level of mother in blood(changes of Zinc in blood of mother from the baseline to 6 months after delivery)
- Zinc level of mother in breast milk(changes of Zinc in breast milk of mother from the delivery day to 6 months after delivery)
- Hemoglobin level of infant(changes of hemoglobin level of infant from the day of birth to 6 months)
- Insulin-like growth factor 1 (IGF-1) of mother(changes of IGF-1 level of mother from the baseline to day of delivery)
- Brain-derived neurotrophic Factor (BDNF) of infant(changes of BDNF level of infant from the day of birth to 6 months)
研究者
Bumi Herman
Assistant Lecturer
Hasanuddin University