Non-invasive Spinal Cord Stimulation for Spasticity Control and Augmentation of Voluntary Motor Control in Individuals With Multiple Sclerosis
Early Phase 1
Completed
- Conditions
- Multiple Sclerosis
- Registration Number
- NCT04486209
- Lead Sponsor
- Medical University of Vienna
- Brief Summary
Epidural spinal cord stimulation (SCS) is currently regarded as one of the most promising intervention methods to improve motor function in individuals with severe spinal cord injury. In parallel, an increasing number of studies is suggesting that noninvasive SCS can improve spasticity and residual motor control in the same subject population. The present study explores whether single sessions of noninvasive SCS would improve walking performance and ameliorate spasticity in individuals with multiple sclerosis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
- confirmed diagnosis of relapsing-remitting, primary- or secondary-progressive MS
- lower-limb spasticity
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Exclusion Criteria
- acute relapse of MS
- other neuromuscular diseases
- active and passive implants at vertebral level T9 or caudally
- dermatological issues at stimulation site
- pregnancy
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Modified Ashworth Scale 24 hours
- Secondary Outcome Measures
Name Time Method Timed up an go test 24 hours 2-min walk test 24 hours 10-m walk test 24 hours
Trial Locations
- Locations (1)
Medical University of Vienna
🇦🇹Vienna, Austria