Quantification of Endo- and Phytocannabinoids With Comparison to Pain Medication Requirements and Surgical Outcomes for Patients Undergoing Abdominal Surgery for Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Postoperative opioid consumption
研究概览
简要总结
To determine how daily cannabis use affects surgical outcomes.
详细描述
To determine if patients who are daily cannabis users that are undergoing inpatient abdominal surgery for the treatment of cancer are different from non-cannabis users regarding phytocannabinoid and endocannabinoid levels, pain scores, pain medication requirements, and surgical complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients > 18 years old
- •Undergoing abdominal surgery for the treatment of cancer
- •Report no cannabis use in the last year or chronic cannabis use (defined as at least weekly use for 3 months or more)
排除标准
- •patients with chronic pain, chronic pain syndrome on opioids
- •female patients who are pregnant or lactating
- •patients who report use of illicit substances
结局指标
主要结局
Postoperative opioid consumption
时间窗: 30 days
Postoperative opioid consumption among daily cannabis using and non-cannabis using patients undergoing abdominal surgery for cancer
Correlation of postoperative complications
时间窗: 30 days
Correlation between 30-day post-operative complications, preoperative, and postoperative phytocannabinoid and endocannabinoid levels
Correlation of postoperative opioid consumption
时间窗: 30 days
Correlation between serum phytocannabinoid and endocannabinoid levels, pain scores, and postoperative opioid consumption
次要结局
未报告次要终点