Coronary Artery Aneurysms: Incidence, Management and Long Term Prognosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,565
- 试验地点
- 1
- 主要终点
- Cardiology readmission
研究概览
简要总结
International registry gathering patients with angiographically confirmed coronary aneurysm.
详细描述
INTRODUCTION AND RATIONALE:
Coronary artery aneurysm is defined as coronary dilatation which exceeds the diameter of normal adjacent segments or the diameter of the patient's largest coronary vessel by 1.5 times. Described by Bourgon, it is an uncommon disease which has been diagnosed with increasing frequency since the advent of coronary angiography. The incidence varies from 1.5% to 5% with male dominance and a predilection for the right coronary artery.
Although several causes have been reported, atherosclerosis accounts for 50% of coronary aneurysms in adults. Reported complications include thrombosis and distal embolization, rupture and vasospasm, causing ischemia, heart failure or arrhythmias. The natural history and prognosis remains obscure, since definitive data are scarce. Controversies persist regarding the use of medical management (antithrombotic) or interventional/surgical procedures.
OBJECTIVES.
Taking into account the classical coronary aneurysm definition, the investigators propose:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Patient ´s refusal to participate.
结局指标
主要结局
Cardiology readmission
时间窗: 12 months
dicotomic variable (yes/no)
Any cause death
时间窗: 12 months
dicotomic variable (yes/no)
次要结局
未报告次要终点
研究者
IVAN J NUÑEZ GIL
MD, PhD, FESC
St Carlos Hospital, Madrid, Spain