Can Guolin Qigong (mind-body exercise) intervention improve fatigue in cancer survivors? A randomized controlled feasibility trial

Not Applicable

Completed

• Conditions: ung cancer; Fatigue; Sleep; Depression; Breast cancer; Colon cancer; Lung cancer; Cancer - Breast; Cancer - Lung - Mesothelioma; Cancer - Lung - Non small cell

• Registration Number: ACTRN12622000688785
• Lead Sponsor: niversity Malaya Medical Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-12
• Study Completion: 2024-01-24
• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

(1) Age equal to or greater than 18 years old); (2) Diagnosed with breast, lung, and colorectal cancer; (3) Able to read and answer questionnaires in English and Bahasa Malaysia language by oneself; (4) Suffering from moderate to severe fatigue as assessed by the simple fatigue scale with a severity score of 3 and above; (5) Able to use smartphones and the WeChat or WhatsApp app; and (6) Able to provide informed consent.

Exclusion Criteria

(1) Cardiopulmonary disease, nerve, muscle, or joint disease, or other malignant tumors affecting physical movement; (2) Mental illness or serious cognitive impairment and defects in language that significantly impairs communication; (3) Post-operative heart, cerebral vessel, or other physical impairment affecting the physical ability to participate in the study; (4) Patients who are not able to legally provide consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility of GQ intervention as a composite primary outcome assessed by recruitment, retention, adherence rate and adverse events (for safety) if any, using a practice diary.<br>However, we do not anticipate any serious adverse events based on past studies of Qigong intervention conducted to improve cancer symptoms or side effects of cancer survivors.[ End of Week-12 intervention.]

Secondary Outcome Measures

Name	Time	Method
Change in Fatigue to be assessed by Brief Fatigue Inventory (BFI)[ Baseline(Week 1),mid-intervention (week-6), post-intervention (Week-12), and 4 weeks after post intervention (Week-16).];Change in Sleep quality to be assessed by Pittsburgh Sleep Quality Index (PSQI)[ Baseline(Week 1),mid-intervention (week-6), post-intervention (Week-12), and 4 weeks after post intervention (Week-16).];Change in Depression to be assessed by Centre for Epidemiologic Studies Depression (CES-D)[ Baseline(Week 1),mid-intervention (week-6), post-intervention (Week-12), and 4 weeks post intervention (Week-16).];Change in 24-hour urine cortisol[ A day prior to enrolment date/baseline (Week1) and post-intervention (Week-12)];Participants' perceptions and experience of GQ.<br>A one-on-one semi-structured interview will be conducted using interview outlines designed specifically for this study.[ Within 3 months after Week-16 (4 weeks post-intervention). ]