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临床试验/NCT07832968
NCT07832968尚未招募不适用

Mulligan Technique Versus Proprioceptive Training in Cervicogenic Headache

Cairo University1 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2026年9月24日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
48
试验地点
1
主要终点
Pain Intensity

研究概览

简要总结

This study will be conducted to compare the effectiveness of mulligan versus proprioceptive training on pain severity, headache disability, flexion rotation test, pain threshold, cervical joint position error in patients with cervicogenic headache.

详细描述

Cervicogenic headache (CGH) is a type of headache, and it occurs commonly due to neck dysfunctions. Many studies found positive association between the neck dysfunction and CGH. The prevalence of this problem is more common in women than men. Headache disorders are classified as primary, such as migraine or tension-type headache, or secondary, such as CGH. The one-year prevalence of CGH in the adult population varies between 0.2 and 2.2%.

It is severely impacts the general public, burdening public health and putting pressure on the local economy and community.

The International Classification of Headache Disorders (ICHD BETA 3) defined cervicogenic headache as "Headache caused by a disorder of the cervical spine and its component bony, disc and/or soft tissue elements, usually but not always accompanied by neck pain.

No drugs are effective for cervicogenic headache. Studies showed that treatment with manual therapy, specific exercises, or manual therapy plus exercises was significantly more effective at reducing headache frequency and intensity than was no treatment. Manual therapy alone, however, was not more effective than exercises alone, and combining the two interventions did not achieve better outcomes than either intervention alone. About 76% of patients achieved a more than 50% decrease in headache frequency and 35% achieved complete relief at the 7-week follow-up. At 12 months, 72% had a more than 50% decrease in headache frequency, but the proportion that had complete relief was not reported.

A recent systematic review concluded that manual therapy may be effective in the short term and neck exercise in the long term in treating adults with cervicogenic headache.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • CGH pain intensity between 3 and 8 on 10-point pain scale.
  • CGH due to cervical spine dysfunction.
  • Reduced cervical motion.
  • Neck pain followed by headache.
  • Unilateral pain starting in the neck and radiating to the frontotemporal region.
  • Reproduction of the headache on palpation of the upper cervical spine (C0 to C3).

排除标准

  • Participants with other types of headache (migraine).
  • Headache due to other causes (sinus, tumor, neural, or temporomandibular joint issues), and any type of physical therapy treatment in the past three months.
  • Any contraindications to manual and manipulative therapy (fracture, instability, osteoporosis, arthropathy, or neural symptoms).
  • Using analgesics or corticosteroids.
  • Metastasis.
  • Cardiac conditions (stroke, hypertension, or syncope).
  • Neurological conditions (radiculopathy, myelopathy, or disc problems).
  • Spinal cord problem.
  • Previous brain and spinal cord surgery.

研究组 & 干预措施

Mulligan Technique + Conventional physical therapy program

Experimental

Participants in this arm will receive Mulligan Mobilization Technique in addition to the conventional physical therapy program. Mulligan techniques will include Headache SNAG, Reverse Headache SNAG, and C1-C2 SNAG rotation. Treatment will be administered for 12 sessions, 3 sessions per week for 4 weeks.

干预措施: Mulligan Technique (Other)

Mulligan Technique + Conventional physical therapy program

Experimental

Participants in this arm will receive Mulligan Mobilization Technique in addition to the conventional physical therapy program. Mulligan techniques will include Headache SNAG, Reverse Headache SNAG, and C1-C2 SNAG rotation. Treatment will be administered for 12 sessions, 3 sessions per week for 4 weeks.

干预措施: Conventional physical therapy program (Other)

Proprioceptive Training + Conventional physical therapy program

Experimental

Participants in this arm will receive proprioceptive training in addition to the conventional physical therapy program. Proprioceptive training will include head relocation practice, cervical joint position retraining using a head-mounted laser pointer, and oculomotor exercises including gaze stability, eye-follow, saccades, and eye-head coordination exercises. Treatment will be administered for 12 sessions, 3 sessions per week for 4 weeks.

干预措施: Proprioceptive Training (Other)

Proprioceptive Training + Conventional physical therapy program

Experimental

Participants in this arm will receive proprioceptive training in addition to the conventional physical therapy program. Proprioceptive training will include head relocation practice, cervical joint position retraining using a head-mounted laser pointer, and oculomotor exercises including gaze stability, eye-follow, saccades, and eye-head coordination exercises. Treatment will be administered for 12 sessions, 3 sessions per week for 4 weeks.

干预措施: Conventional physical therapy program (Other)

结局指标

主要结局

Pain Intensity

时间窗: 4 weeks

Pain intensity will be assessed using the Visual Analogue Scale (VAS). Participants will rate their pain intensity on a 10-cm scale, where 0 indicates no pain and 10 indicates maximum intolerable pain.

Headache Impact

时间窗: 4 weeks

Headache impact will be assessed using the Arabic version of the Headache Impact Test-6 (HIT-6). The total score ranges from 36 to 78, with higher scores indicating a greater impact of headache on daily functioning.

Right Cervical Flexion-Rotation Range of Motion

时间窗: 4 weeks

Right cervical flexion-rotation range of motion will be assessed using the Cervical Range of Motion (CROM) instrument during the Flexion-Rotation Test (FRT). Rotation will be measured in degrees for the right side.

Left Cervical Flexion-Rotation Range of Motion

时间窗: 4 weeks

Left cervical flexion-rotation range of motion will be assessed using the Cervical Range of Motion (CROM) instrument during the Flexion-Rotation Test (FRT). Rotation will be measured in degrees for the left side.

Pressure Pain Threshold

时间窗: 4 weeks

Pressure pain threshold (PPT) will be assessed using a digital algometer. Measurements will be obtained over the upper trapezius muscle, C2-C3 zygapophyseal joint, suboccipital muscles bilaterally, and tibialis anterior muscle area. The mean of three trials at each measurement site will be used for analysis.

次要结局

  • Cervical Joint Position Error(4 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nada helmy mohamed

Principal Investigator

Cairo University

研究点 (1)

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