An Exercise Intervention on Metabolic Syndrome and Prostate Cancer Risk Among Black Men
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Waist circumference
研究概览
简要总结
The main purpose of this study is to examine the feasibility of an exercise intervention on metabolic syndrome (MetS) components and biomarkers related to prostate cancer in Black men with MetS who are at increased risk of prostate cancer.
详细描述
The specific aim for the proposed study is to examine the feasibility and impact of a 6-month two-arm randomized controlled trial (RCT) on MetS components and biomarkers related to prostate cancer in Black men with MetS. Due to the striking racial disparities of prostate cancer, this proposal will focus on the impact of an aerobic and resistance exercise intervention on MetS and biomarkers related to prostate cancer in Black men. Specifically, our proposed clinical trial compares an aerobic and resistance exercise intervention to an attention control group among Black men.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •African-American and/or Black men;
- •between the ages of 40-70 years;
- •waist circumference >40 inches (102 cm);
- •with at least two of the following: elevated BP (≥ 130/85 mmHg);
- •elevated fasting glucose (≥ 100 mg/dL), reduced HDL cholesterol (<50 mg/dL), or elevated triglycerides (≥ 150 mg/dL);
- •sedentary defined as <60 minutes of recreation or work requiring modest PA/week;
- •be able to speak and read English;
- •able to provide meaningful consent (i.e., men with severe cognitive impairment will be excluded);
- •have no physical limitations that prevent from exercising;
- •and have access to a television and DVD player.
排除标准
- •history of cancer except nonmelanoma skin cancer;
- •current enrollment in another clinical trial or weight loss program;
- •inability to commit to the intervention schedule. Prior to randomization, participants will be required to have a signed authorization and medical clearance from their personal physician or our nurse practitioner.
结局指标
主要结局
Waist circumference
时间窗: 6-months
Waist circumference will be measured at baseline, 3- and 6-months of the intervention
次要结局
- Cardiovascular fitness test(6-months)
- Fasting glucose levels test(6-months)
- Body Mass Index (BMI)(6-months)
- Lipid level test(6-months)
- Dietary behaviors questionnaire(6-months)
- Quality of life questionnaire (SF-36)(6-months)