Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma
- Conditions
- Recurrent Laryngeal Carcinoma
- Registration Number
- NCT03604601
- Lead Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
- Brief Summary
Early laryngeal cancer can be treatment by laser surgery or radiotherapy, intermediate and advanced laryngeal carcinoma mainly surgical treatment. Laryngeal cancer is at risk of recurrence after treatment, whether in surgery, laser or radiotherapy. The recurrence rate of laryngeal cancer is about 10% reported at home and abroad. Local pain, ulcers, breathing and eating difficulties caused by recurrent laryngeal cancer seriously reduce the quality of life of patients and seriously endanger their lives. Therefore, head and neck surgeons are required to make every effort to give them saving treatment in order to improve their quality of life. Prolong the patient's life.
- Detailed Description
medical records and extracted information including age, gender, initial treatment modality of glottis cancer, recurrence time, recurrence site, histopathology, tumor grade according to World Health Organization (WHO) grade and tumor stage. Stages were defined according to the American Joint Committee on Cancer (AJCC) staging system.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 54
- more than 18 years,
- patients with recurrent glottic laryngeal squamous cell carcinoma undergoing salvage surgery
- postoperative radiotherapy and chemotherapy
- loss to follow-up
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method overall survival (OS) Follow up 5 years The overall survival rate was calculated with Kaplan-Meier method.
- Secondary Outcome Measures
Name Time Method