The effects of 6% hydroxyethyl starch on ischemia-reperfusion injury in total knee replacement surgery with tourniquet applicatio
Not Applicable
Recruiting
- Conditions
- 6% hydroxyethyl starch, tourniqutte application, total knee arthroplasty, ischemic-reperfusion syndrome
- Registration Number
- JPRN-UMIN000022380
- Lead Sponsor
- ational Health Insurance Corporation Ilsan Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
emergency surgery uncontrolled hypertension, diabetes ASA class III, IV
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference of serum malondialdehide level before and after tourniqutte application in each group, 6% hydroxyethyl starch group and normal saline group.
- Secondary Outcome Measures
Name Time Method Differences of serum malondialdehide between the groups, 6%hydroxyethyl starch and normal saline group before and after tourniqutte application. Differences of serum total protein, albumin level between two groups before and after tourniqutte application.