Estimation of the activity of marker enzymes ( Paraoxonase 1,Myeloperoxidase) in serum and their relationship with Atherogenic Index of Plasma in patients with abnormal lipid levels
Not Applicable
Completed
- Conditions
- Health Condition 1: I709- Other and unspecified atherosclerosis
- Registration Number
- CTRI/2019/01/017177
- Lead Sponsor
- Tejal Deepak Durgekar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 143
Inclusion Criteria
1. Healthy controls with normal lipid profile.
2.Patients having dyslipidemia with and without cardiovascular complications will be included.
Exclusion Criteria
1. Patients with renal failure, chronic Kidney Disease, triglycerides levels greater than 500 mg/dl, diabetes with glycated Hemoglobin greater than 9 will be excluded.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measuring serum Paraoxonase 1(PON1) , Myeloperoxidase(MPO) activity, Atherogenic Index of Plasma (AIP), Effect of Statin therapy on PON1, MPO and AIPTimepoint: six months
- Secondary Outcome Measures
Name Time Method Assessing risk prediction of cardiovascular disease.Timepoint: six months