ISRCTN37109430已完成未知
A study to find the optimal dose for vitamin K supplementation in patients being treated with vitamin K antagonists to create an anti-coagulation effect
etherlands Heart Foundation (Nederlandse Hartstichting) (The Netherlands)0 个研究点目标入组 400 人开始时间: 2008年3月31日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 400
研究概览
简要总结
2011 results in https://pubmed.ncbi.nlm.nih.gov/21193422/ (added 23/10/2020)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Start treatment with vitamin K antagonists less then four weeks before inclusion
- •2. Treatment with vitamin K antagonists for a minimal period of six months, with the therapeutic range of International normalised ratio (INR) between 2.5 anf 3.5
- •3. Aged between 18 and 85 years, either sex
- •4. Measurement of the INR by the Thrombosis Service Leiden
- •5. Informed consent
排除标准
- •1. Treatment for liver failure
- •2. Dialysis, both peritoneal and haemodialysys
- •3. Pregnancy, or wish to get pregnant; lactational period
- •4. Known to have a chronic condition with a life expectancy of less than six months
- •5. An expected interruption of treatment with oral anti-coagulants for one week or longer
- •6. Participation in the self-management protocol
研究者
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