Comparison of Intravitreal Bevacizumab and Triamcinolone With Placebo

Phase 1

• Conditions: Acute Nonarteritic Anterior Ischemic Optic Neuropathy
• Interventions: Other: placebo; Drug: Avastin and Triamcinolone

• Registration Number: NCT01330524
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

In this study 16 Patients diagnosed with Nonarteritic Anterior Ischemic Optic Neuropathy(NSION) who had a sudden mono ocular vision loss associated with optic disc edema and positive Marcus Gunn in less than 30 days without exclusion criteria are randomly divided in two groups 1) control 2) case. In case group Avastin and Triamcinolone will be injected trough vitreal and placebo will be injected in control group. BCVA and Visual field will be then measured in these two groups.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-11
• Study Start: 2010-01
• Primary Completion: 2010-11
• Study First Submitted: 2011-03-08
• Study First Submitted QC: 2011-04-05
• Last Update Submitted: 2011-04-05
• Study First Posted: 2011-04-07
• Last Update Posted: 2011-04-07
• Study Completion: 2011-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	placebo	-
Avastin and Triamcinolone	Avastin and Triamcinolone	-

Primary Outcome Measures

Name	Time	Method
Changes of Best corrected visual acuity(BCVA)	6 month	outcome method of measurement: Snellen chart

Secondary Outcome Measures

Name	Time	Method
Changes of Visual Field	6 month	Automated perimeter

Trial Locations

Locations (1)

Labbafinejad medical center; 🇮🇷 Tehran, Iran, Islamic Republic of