Cardiac autonomic dysfunction in diabetic patients undergoing major surgeries
Not Applicable
- Conditions
- Health Condition 1: E088- Diabetes mellitus due to underlying condition with unspecified complications
- Registration Number
- CTRI/2023/08/055943
- Lead Sponsor
- AIIMS Kalyani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult Diabetic patients scheduled for major elective surgeries.
Exclusion Criteria
Cardiac rhythm other than sinus rhythm, Parkinson’s disease, idiopathic orthostatic hypotension, Shy-Drager syndrome, Addison’s disease and hypopituitarism, pheochromocytoma, peripheral autonomic neuropathy, cardiomyopathy, and proven or suspected allergy for any of the medication used during induction of anaesthesia.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Prevalence of cardiac autonomic dysfunction in patients coming to Pre anaesthesia clinic with known or newly diagnosed diabetes mellitusTimepoint: 1.Baseline
- Secondary Outcome Measures
Name Time Method 1.Hemodynamic response to induction of anaesthesia, laryngoscopy, intubation, extubation in patients with Cardiac autonomic dysfunction <br/ ><br>(CAN). <br/ ><br>2.Incidence, duration & severity of intraoperative hypotension & hypertension & requirement of pharmacological intervention in patients with CAN. Severe hypotension will defined as a mean arterial pressure (MAP) of less than 50 mmHg or a 30 percent decrease in MAP from baseline. Severe hypertension will defined as a mean arterial pressure (MAP) of more than 50 mmHg or a 30 percent increase in MAP from baseline <br/ ><br>3.Major Adverse Cardiac Events new onset myocardial ischemia, congestive cardiac failure, cardiac arrhythmias, cardiac arrest requiring resuscitation in patients with CAN. <br/ ><br>4.Duration of hospital stay & in hospital motality <br/ ><br>6.Ultrasound assessment of gastric content & volume.Timepoint: During surgery. <br/ ><br>After surgery till the patient is discharged <br/ ><br>