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Clinical Trials/NCT02652689
NCT02652689
Terminated
Not Applicable

Transthoracic Parametric Doppler Assessment of Lung Doppler Signals in Acute Pulmonary Embolism

Echosense Ltd.1 site in 1 country25 target enrollmentApril 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pulmonary Embolism
Sponsor
Echosense Ltd.
Enrollment
25
Locations
1
Primary Endpoint
Identify lack of Lung Doppler signals in specific lung sections that were diagnosed obstructed by CT
Status
Terminated
Last Updated
7 years ago

Overview

Brief Summary

The LDS may contain information of significant diagnostic and physiological value regarding the pulmonary parenchyma and vasculature, as well as the cardio- vascular system in general. In pilot clinical studies of patients with acute decompensated heart failure (ADHF) as well as patients with Pulmonary Hypertension, LDS signals patterns unique to these conditions were identified. We believe that these newly discovered ultrasound signals might provide a non-invasive radiation-free means to diagnose and monitor patients with Pulmonary Embolism.

The purpose of this study is to assess the utility of noninvasive assessment of lung Doppler signals performed via transthoracic parametric Doppler. The objective of the study is to evaluate the lung Doppler signals (LDS) in patients diagnosed with acute PE, in order to determine the potential assessment value of this non-invasive method in this potentially life threatening condition.

Registry
clinicaltrials.gov
Start Date
April 2016
End Date
January 2019
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Confirmed diagnosis of acute PE on CTA

Exclusion Criteria

  • Pregnant women
  • Inability to consent
  • Patients with severe chest wall deformity
  • Previously diagnosed PE
  • Pneumonia
  • Pulmonary edema
  • Pneumothorax
  • Severe COPD (gold class III, IV)
  • Hemodynamically unstable patients

Outcomes

Primary Outcomes

Identify lack of Lung Doppler signals in specific lung sections that were diagnosed obstructed by CT

Time Frame: 30min

The obstructed sections will be compared with healthy lung sections

Study Sites (1)

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