Transthoracic Parametric Doppler Assessment of Lung Doppler Signals in Acute Pulmonary Embolism
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Identify lack of Lung Doppler signals in specific lung sections that were diagnosed obstructed by CT
研究概览
简要总结
The LDS may contain information of significant diagnostic and physiological value regarding the pulmonary parenchyma and vasculature, as well as the cardio- vascular system in general. In pilot clinical studies of patients with acute decompensated heart failure (ADHF) as well as patients with Pulmonary Hypertension, LDS signals patterns unique to these conditions were identified. We believe that these newly discovered ultrasound signals might provide a non-invasive radiation-free means to diagnose and monitor patients with Pulmonary Embolism.
The purpose of this study is to assess the utility of noninvasive assessment of lung Doppler signals performed via transthoracic parametric Doppler. The objective of the study is to evaluate the lung Doppler signals (LDS) in patients diagnosed with acute PE, in order to determine the potential assessment value of this non-invasive method in this potentially life threatening condition.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of acute PE on CTA
排除标准
- •Pregnant women
- •Inability to consent
- •Patients with severe chest wall deformity
- •Previously diagnosed PE
- •Pneumonia
- •Pulmonary edema
- •Pneumothorax
- •Severe COPD (gold class III, IV)
- •Hemodynamically unstable patients
研究组 & 干预措施
Diagnostic ultrasound
Recording Doppler ultrasound signals noninvasively from the right chest wall
干预措施: Diagnostic ultrasound radiation (Radiation)
结局指标
主要结局
Identify lack of Lung Doppler signals in specific lung sections that were diagnosed obstructed by CT
时间窗: 30min
The obstructed sections will be compared with healthy lung sections
次要结局
未报告次要终点