Stroke Cincinnati Prehospital Stroke Severity Scale Evaluation iN prEhospital

Completed

• Conditions: Stroke
• Interventions: Diagnostic Test: Questionnaire

• Registration Number: NCT03181412
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

The effectiveness of acute ischemic stroke (AIS) management has improved considerably in recent years with thrombolysis and more recently with mechanical thrombectomy (MT). Currently, mechanical thrombectomy can only be performed in stroke unit with an interventional neuroradiology center by experienced/qualified interventional neuroradiologists. In the Rhone area, only one hospital has the authorization to perform mechanical thrombectomy. Therefore, transferring directly eligible acute ischemic stroke patients for mechanical thrombectomy to this center constitutes an important stake of the triage of suspected acute ischemic stroke patients. Some validated scores for the identification of severe strokes and large vessel occlusion, including the Cincinnati prehospital stroke severity scale (CPSSS), appear to be relevant for pre-hospital use in order to identify patients potentially eligible for mechanical thrombectomy and address them to a stoke unit with interventional radiology center.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-06-07
• Study First Submitted QC: 2017-06-07
• Study First Posted: 2017-06-08
• Study Start: 2018-06-25
• Primary Completion: 2022-01-31
• Study Completion: 2022-01-31
• Status Verified: 2022-11
• Last Update Submitted: 2022-11-18
• Last Update Posted: 2022-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1272

Inclusion Criteria

• Consecutive patients calling emergency medical services for suspected acute ischemic stroke

Exclusion Criteria

• Symptom onset (or the last time the patient was seen without deficit ) of more than 6 hours

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with suspected ischemic stroke	Questionnaire	The cohort will be constituted of patients treated for a stroke suspicion after calling emergency medical services of the Rhone and presenting a symptom-onset (the last time the patient was seen without deficit) less than 6 hours.

Primary Outcome Measures

Name	Time	Method
Performances of Cincinnati prehospital stroke severity scale	1 day	The Cincinnati prehospital stroke severity scale is composed of 3 items: 2 points if the patient has a deviation of the gaze, 1 point if the patient is not able to give the date and answer to a simple order such as closing the eyes or clenching the fist and 1 point if the patient presents a hemiplegia. The CPSSS score ranges from 0 to 4, highest value indicating the worst score. It will be considered positive if it is equal to 2 or more.; Performances will be evaluated in terms of sensitivity, specificity, positive and negative predictive values.

Trial Locations

Locations (12)

Urgentiste, Centre Hospitalier Lyon Sud; 🇫🇷 Pierre-Bénite, France

Médecine d'urgence, Hôpital Nord-Ouest; 🇫🇷 Tarare, France

Médecine d'urgence, Hôpital Mutualiste Médipôle; 🇫🇷 Lyon, France

Services Neurologie et Médecine d'urgence, CH de Villefranche sur Saône; 🇫🇷 Villefranche-sur-Saône, France

Médecine d'urgence, CH de Roanne; 🇫🇷 Roanne, France

SAMU 69 , Hôpital Edouard Herriot; 🇫🇷 Lyon, France

Médecine d'urgence, Hôpital Desgenettes; 🇫🇷 Lyon, France

Médecine d'urgence, Clinique de la Sauvegarde; 🇫🇷 Lyon, France

Neurologie, Hôpital Neurologique - HCL; 🇫🇷 Bron, France

Médecine d'urgence, Hôpital Saint Joseph Saint Luc; 🇫🇷 Lyon, France

Médecine d'urgence, Hôpital de la Croix-Rousse - HCL; 🇫🇷 Lyon, France

Services Médecine d'urgence et Neurologie, CH de Vienne; 🇫🇷 Vienne, France