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Clinical Trials/NCT07316673
NCT07316673
Not yet recruiting
Not Applicable

A Prospective Randomized Clinical Trial Comparing a Fast Fix Enhanced Arthroscopic System Versus Conventional Arthroscopic Suturing for Temporomandibular Disc Repositioning in Internal Derangement: Clinical, Functional, and Surgical Outcomes

Cairo University0 sites50 target enrollmentStarted: January 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
50
Primary Endpoint
Functional improvement assessed by Maximum Mouth Opening (MIO)

Overview

Brief Summary

This prospective randomized clinical trial evaluates the effectiveness of a Fast Fix-enhanced arthroscopic system compared with conventional arthroscopic suturing for temporomandibular joint disc repositioning in patients with TMJ internal derangement. Patients are randomly allocated into two groups and assessed for functional improvement (maximum mouth opening), pain reduction, joint symptoms, and surgical performance outcomes over a 6-month follow-up period. The study aims to determine whether the Fast Fix-enhanced technique provides superior clinical, functional, and surgical outcomes compared to conventional arthroscopic suturing

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
15 Years to 75 Years (Child, Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age ≥ 18 years.
  • Both sexes.
  • Patients with TMJ internal derangement (disc displacement without reduction).
  • Patients indicated for arthroscopic disc repositioning following failure of conservative management.

Exclusion Criteria

  • Previous TMJ surgery on the affected joint.
  • Rheumatoid arthritis, systemic inflammatory joint disease, or other TMJ pathology (tumor, fracture, infection)
  • Severe degenerative joint disease (osteoarthritis grade V) or ankylosis.
  • Patients are unable to comply with follow-up assessments or MRI evaluation.
  • Patients with TMDS are secondary to malocclusion.

Arms & Interventions

Fast-Fix-Enhanced Arthroscopic Disc Repositioning

Experimental

Intervention: Fast-Fix-Enhanced Arthroscopic (Procedure)

Conventional Arthroscopic Suturing Disc Repositioning

Active Comparator

Intervention: (Conventional Arthroscopic Suturing Disc Repositioning) (Procedure)

Outcomes

Primary Outcomes

Functional improvement assessed by Maximum Mouth Opening (MIO)

Time Frame: Baseline (preoperative) to 6 months postoperatively (with assessments at 3 months and 6 months; primary endpoint at 6 months

MIO is measured as the maximal interincisal distance (in millimeters) using a ruler or digital caliper, with the primary endpoint being the change from baseline to 6 months postoperatively.

Secondary Outcomes

  • Clinical outcomes , Pain reduction assessed using the Visual Analogue Scale (VAS) • Improvement of joint symptoms, including clicking and tenderness.(Baseline (preoperative), 3 months, and 6 months postoperatively)
  • Joint Symptoms (Clicking and Tenderness)(Baseline (preoperative), 3 months, and 6 months postoperatively)
  • Surgical outcomes Total surgical time recorded(Intraoperative (day of procedure only))
  • surgical outcomes Technical Feasibility(Intraoperative (day of procedure only))

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Wajmah Sayed Karim Al Sayed

Principal Investigator

Cairo University

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