The Relationship Between Nocturnal Enuresis And Spina Bifida Occulta

Completed

• Conditions: Enuresis, Nocturnal; Spina Bifida

• Registration Number: NCT03543995
• Lead Sponsor: Ankara Training and Research Hospital

Brief Summary

It is claimed that SBO may be responsible for bladder dysfunction in patients without known neurological disease. Subsequently, it was reported that the frequency of SBO in NE cases was higher than normal children. However, in controlled trials, SBO frequency was not different in NE patients compared to the normal population. Conversely, the incidence of dysfunctional bladder in the presence of SBO in NE patients was found to be higher and the response to treatment was worse than in non-SBO patients.

The present study aimed to determine whether the frequency of SBO in patients with NE was higher than in healthy subjects, the effect of SBO on the severity of LUTS and whether treatment response of primary NE patients changed in the presence of SBO.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2017-12-31
• Status Verified: 2018-05
• Study Completion: 2018-05-15
• Study First Submitted: 2018-05-22
• Study First Submitted QC: 2018-05-31
• Last Update Submitted: 2018-05-31
• Study First Posted: 2018-06-01
• Last Update Posted: 2018-06-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 330

Inclusion Criteria

• Patients aged 6 to 15 years
• at least one night-time wetting weekly

Exclusion Criteria

• neurological disease,
• diabetes mellitus or insipidus,
• spinal surgery history, spina bifida skin findings,
• chronic renal insufficiency
• and secondary enuresis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dry bed days	3 months	Patients were called for check-up one and three months later. When waking in the morning they were given a form to mark as dry or wet, and dry bed days were examined at check-up.