Silent Hypoxia and Awake Proning in COVID-19 Patients: Home Monitoring and Self-Reporting
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Association between silent hypoxia and other subjective and objective measurements of disease severity
研究概览
简要总结
The Investigators want to examine patients infected with SARS-CoV-2 for the phenomenon "Silent Hypoxia", which is clinically significant hypoxia without corresponding degree of dyspnea. The patient population is infected individuals without any serious symptoms and is at home. The participants will be equipped with a pulse oximeter and a PEF-measurement device. Four times daily the participants will register saturation, degree of dyspnea and PEF. If the participants experience desaturation or increasing dyspnea, physiotherapy is to be performed, and if that doesn't relieve symptoms or increase oxygen saturation, the hospital should be contacted for admission. The first part of this study is a feasibility study, and if found feasible, the investigators will expand the study to more participants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non dyspneic (NRS =/< 1) patients with positive SARS-CoV-2 test
- •Age 18 - 80 years
- •Patients managed at home
- •Inclusion within 72 hours from positive test
排除标准
- •Chronic hypoxia (SpO2 < 93 %) and/or first measured SpO2 < 93 %
- •Admitted to hospital for COVID-19 prior to inclusion
- •Unable to perform pulse oximetry
- •Unable to perform physiotherapy
研究组 & 干预措施
Self measurement of peripheral saturation
Participant will be equipped with a pulse oximeter and perform saturation measurements.
干预措施: Self measurement with pulse oximeter (Other)
结局指标
主要结局
Association between silent hypoxia and other subjective and objective measurements of disease severity
时间窗: January 30, 2021
Number of patients who manage to perform daily measurements of SpO2
时间窗: January 30, 2021
Incidence rate of silent hypoxia in non-hospitalized COVID-19
时间窗: January 30, 2021
次要结局
- Effect of a self-managed physiotherapy program on alleviating hypoxia(January 30, 2021)
- Rate of hospital admission and ICU admission(January 30, 2021)
- Incidence of thromboembolic event in outpatients diagnosed with COVID-19(January 30, 2021)
- Rate of persistent silent hypoxia episode per patients(January 30, 2021)
- Rate of silent hypoxia episode per patients(January 30, 2021)
研究者
Hans Joakim Myklebust-Hansen
Konstituert Overlege, Akuttseksjonen
Ostfold Hospital Trust