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Clinical Trials/NL-OMON54043
NL-OMON54043
Recruiting
Not Applicable

Aerobic fitness or Muscle mass training to Improve Colorectal cancer Outcomes (AMICO): to study safe and feasible exercise dosages (phase 2) and the effects of exercise on chemotherapy dose modifications and progression free survival (phase 3) in patients with metastatic colorectal cancer. - AMICO

Radboud Universitair Medisch Centrum0 sites228 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Radboud Universitair Medisch Centrum
Enrollment
228
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Eligibility Criteria

Inclusion Criteria

  • \-age \>\=18 years;
  • \-mCRC with indication for chemotherapy, with initially unresectable metastatic
  • \-scheduled for treatment with first\-line doublet or triplet chemotherapy,
  • according to the national guideline
  • \-able and willing to give written informed consent.

Exclusion Criteria

  • \-life expectancy \<6 months
  • \-unable to perform basic activities of daily living such as walking or biking
  • \-presence of cognitive disorders or severe emotional instability (e.g.,
  • Schizophrenia, Alzheimer, alcohol addiction);
  • \-presence of other disabling co\-morbidities that might hamper physical exercise
  • (e.g. heart failure (NYHA classes 3 and 4\), chronic obstructive pulmonary
  • disease (COPD, gold 3 and 4\), orthopaedic conditions and neurological disorders
  • (e.g., hernia, paresis, amputation, active rheumatoid arthritis);
  • \-insufficient mastery of the Dutch language;
  • \-presence of serious cardiovascular or cardiopulmonary conditions (e.g.

Outcomes

Primary Outcomes

Not specified

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