Investigation of Genetic Risk of Atrial Fibrillation

• Conditions: Atrial Fibrillation

• Registration Number: NCT00412438
• Lead Sponsor: Nagoya University

Brief Summary

The atrial fibrillation (AF) is the most common cardiac rhythm disturbance that is responsible for substantial morbidity and mortality independent of associated heart disease or other risk factors. Even in the absence of preexisting cardiovascular disease, AF remains significantly associated with excess mortality rates. The current unsatisfactory treatment for AF comes from lack of understanding of the pathophysiology of AF. The purpose of this study is to identify gene polymorphisms that confer susceptibility to atrial fibrillation. Patients with AF（N=500） and healthy volunteer（N=1000） without AF are enrolled in this study. Patients with coronary artery disease, severe valvular heart disease, cardiomyopathy or heart failure were excluded from the study.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-10
• Status Verified: 2006-12
• Study First Submitted: 2006-12-15
• Study First Submitted QC: 2006-12-15
• Last Update Submitted: 2006-12-15
• Study First Posted: 2006-12-18
• Last Update Posted: 2006-12-18

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Clinical diagnosis of atrial fibirillation

Read More

Exclusion Criteria

• coronary artery disease
• severe valvular heart disease
• cardiomyopathy
• heart failure

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Department of Bio-information Analysis, Research Institute of Enviromental Medicine, Nagoya University; 🇯🇵 Nagoya, Aichi, Japan