A study of booster-dose influenza vaccination responses compared to standard-dose in lupus patients: an open labeled, randomized controlled study

Mahidol university0 个研究点目标入组 109 人开始时间: 2023年6月10日最近更新: 2024年8月19日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方: Mahidol university
入组人数: 109

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

In conclusion, booster dose influenza vaccination may increase seroconversion in some strains (H1N1 and B/Victoria), especially in patients who received high levels of immunosuppression. However, there were no clinical differences in the incidence of influenza infection between the SD and BD regimens. Further studies on a larger scale are necessary.

研究设计

研究类型: Interventional

入排标准

年龄范围: 18 Years 至 50 Years（—）
性别: All

入选标准

•1. Lupus patients diagnosed by the 2019 European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) SLE Classification criteria, 2. Under the care of rheumatologists at the rheumatology clinic of Ramathibodi Hospital

排除标准

•1. Pregnancy, 2. Active cancer, 3. Positive HIV status, 4. Prior history of organ transplant, 5. Receipt of influenza vaccine or prior history of an influenza infection within six months, 6. Evidence of CMV infection within three months, 7. Known history of severe allergic reaction to influenza vaccine

研究者

发起方

Mahidol university

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