Laparoscopic Segmental Bowel Resection for Deep Infiltrating Colorectal Endometriosis

Completed

• Conditions: Endometriosis
• Interventions: Procedure: multidisciplinary laparoscopy; Other: Questionnaires

• Registration Number: NCT00462176
• Lead Sponsor: University Hospital, Gasthuisberg

Brief Summary

This study is executed to evaluate the outcome on quality of life, pain, sexuality, pregnancy rate and recurrence rate after a fertility sparing multidisciplinary CO2 laser laparoscopic radical excision of deep infiltrating colorectal endometriosis with a bowel resection.

Detailed Description

Patients

All women (n=45) who had undergone fertility sparing CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with bowel resection were selected retrospectively from the list of all patients (n=more than 500, of whom slightly more than 50% with endometriosis) operated at the Leuven University Fertility Centre (LUFc) between September 2004 and September 2006.

Questionnaires

All 45 patients were asked to complete the Oxford Endometriosis Quality of Life questionnaire (27), a sexual activity questionnaire (28), visual analogue scales (VAS) for dysmenorroe, chronic pelvic pain and deep dyspareunia, and to answer questions about medication and fertility, to compare their status before surgery and at the moment of the evaluation (December 2008).

Study Timeline

• Study Start: 2004-09
• Study First Submitted: 2007-04-17
• Study First Submitted QC: 2007-04-17
• Study First Posted: 2007-04-18
• Primary Completion: 2008-02
• Study Completion: 2008-02
• Status Verified: 2009-02
• Last Update Submitted: 2009-02-19
• Last Update Posted: 2009-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 45

Inclusion Criteria

• Patients suffering from deep infiltrating endometriosis with colorectal extension
• Who had undergone CO2 laser laparoscopic radical excision of the endometriosis
• with bowel resection performed by the colorectal surgeon
• between September 2004 and July 2006.

Exclusion Criteria

• Patients without bowel resection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
1	Questionnaires	All women (n=45) who had undergone CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with active involvement of the colorectal surgeon performing a bowel resection were selected retrospectively from the list of all patients (n=more than 400) operated at the Leuven University Fertility Centre (LUFc) between September 2004 and July 2006.
1	multidisciplinary laparoscopy	All women (n=45) who had undergone CO2 laser laparoscopic radical excision of deep infiltrating endometriosis with active involvement of the colorectal surgeon performing a bowel resection were selected retrospectively from the list of all patients (n=more than 400) operated at the Leuven University Fertility Centre (LUFc) between September 2004 and July 2006.

Primary Outcome Measures

Name	Time	Method
Pain; Sexuality; Quality of life; Fertility rate; Complication rate; Recurrence rate	a median follow-up of 27 months (range 16 - 40 months) after surgery

Secondary Outcome Measures

Name	Time	Method
Economic life circumstances	a median follow-up of 27 months (range 16 - 40 months) after surgery

Trial Locations

Locations (1)

University Hospital Gasthuisberg; 🇧🇪 Leuven, Belgium