Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2

Not Applicable

Completed

• Conditions: Chronic Periodontitis
• Interventions: Procedure: Scaling & root planning alone; Procedure: Periodontal treatment with Hyaluronic acid associated with SRP

• Registration Number: NCT03807596
• Lead Sponsor: Cairo University

Brief Summary

The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling \& root planing (SRP) in patients with chronic periodontitis \& diabetes mellitus type 2.

Detailed Description

Thirty subjects with chronic periodontitis \& diabetes mellitus type 2 were included in this randomized clinical trial. These subjects were randomly allocated into test \& control equal groups. The test group comprised fifteen patients who received SRP with subgingival application of Hyaluronic acid as an adjunct. The control group included fifteen patients who received SRP alone. Plaque index (PI), gingival index (GI), probing depth (PD) \& clinical attachment level (CAL) were measured \& documented at baseline, 6 weeks \& 12 weeks intervals.

Study Timeline

• Study Start: 2017-03-16
• Primary Completion: 2017-06-29
• Study Completion: 2017-06-29
• Status Verified: 2019-01
• Study First Submitted: 2019-01-15
• Study First Submitted QC: 2019-01-15
• Last Update Submitted: 2019-01-16
• Study First Posted: 2019-01-17
• Last Update Posted: 2019-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients with chronic periodontitis and type 2 diabetes mellitus
• Minimum of 20 teeth
• Clinical attachment level (CAL) ≥ 3 mm
• Probing depth (PD) ≥ 4 mm.

Exclusion Criteria

• Pregnant females
• Smokers

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
SRP group	Scaling & root planning alone	Chronic periodontitis patients with type 2 diabetes mellitus recieved Periodontal treatment in the form of scaling \& root planing (SRP) alone.
Hyaluronic acid & SRP group	Periodontal treatment with Hyaluronic acid associated with SRP	Chronic periodontitis \& type 2 diabetes mellitus patients received Periodontal treatment in the form of scaling \& root planing (SRP) with the adjunctive use of hyaluronic acid.

Primary Outcome Measures

Name	Time	Method
Gain in clinical attachment level	12 weeks	Gain in clinical attachment level will be measured in millimeter by William's graduated periodontal probe

Trial Locations

Locations (1)

Faculty of Dentistry, Cairo University; 🇪🇬 Cairo, Egypt